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Ciproxin has been known to cause effects on the liver such as inflammation hepatitis and yellow jaundice, which may rarely progress to life-threatening hepatic failure. This leaflet does not tell you everything about your medicine. Never give this medicine to other people, it may harm them, even if their symptoms are the same as yours. STORING YOUR MEDICINE Keep out of the reach and sight of children No special precautions are required IMPORTANT Remember this medicine is for you. Ciproxin may cause joint or tendon swelling with pain which may lead to tendon rupture especially of the large tendon at the back of the ankle. Take the tablets as prescribed by your doctor.. Your doctor may check your blood for signs of liver problems. He/she will have additional information about this medicine and will be able to advise you. EXPIRY DATE Do not use this medicine after the expiry date shown on the carton label or blister strip. If you think you are affected consult your doctor. If you are taking the Ciproxin Tablets on an empty stomach, do not eat or drink dairy products such as milk or yoghurt or drinks with added calcium at the same time as the tablets. Impaired sense of taste and smell have also been reported; these usually return to normal once treatment with Ciproxin finishes. If you suffer from the medical condition myasthenia gravis a rare disorder of the nervous system, taking Ciproxin may rarely, make the symptoms of your disease become worse.Pseudomembranous colitis can happen with most antibiotics, including Ciprofloxacin Tablets. Do not take the next dose of Ciproxin tablets unless your doctor tells you to. Call your healthcare provider right away if you get watery diarrhea, diarrhea that does not go away, or bloody stools. The duration of treatment for lung infection in children or adolescents with cystic fibrosis is 10 - 14 days. If you experience these symptoms, seek medical advice immediately and rest the affected limb. If you notice yellowing of your skin or any change in your urine output or appearance, possibly accompanied by kidney pain, or pain in your abdomen or back, seek medical advice immediately. Usually this will be one tablet taken twice daily. Prothrombin time and INR should be monitored frequently during and shortly after co-administration of ciprofloxacin with an oral anticoagulant for example, warfarin. It may also cause effects on the kidney which lead to pain and discomfort when passing water crystalluria or blood in the urine. If your tablets become discoloured or show any other signs of deterioration, consult your pharmacist who will tell you what to do. It is important that you complete the course of treatment, even if you begin to feel better after a few days. The tablets should be swallowed whole with a glass of water. The risk may vary with the underlying infection, age and general status of the patient so that the contribution of ciprofloxacin to the increase in INR international normalized ratio is difficult to assess. Take the tablets for as long as directed by your doctor. Pseudomembranous colitis can happen 2 or more months after you have finished your antibiotic. It may cause inflammation of the pancreas, which may lead to severe pain in the upper abdomen or back. The usual duration of treatment is between 3 and 10 days, but it may be longer if your infection is more persistent or severe. You may have stomach cramps and a fever. If you have any questions or are not sure about anything, ask your doctor or pharmacist. YOUR DOCTOR WILL GIVE YOU ADVICE. If your doctor tells you to stop taking this medicine, return any unused tablets to your pharmacist for safe disposal. Drink several more glasses of water during every day of your treatment, unless told otherwise by your doctor. Ciproxin can also cause muscle pain, increased muscle tone, weakness or twitching.Simultaneous administration of ciprofloxacin with an oral anticoagulantmay augment the effect of the anticoagulant. The duration of treatment in patients with anthrax is 60 days. 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