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Misoprostol 600. See Patient Information at the end of this labeling. The alpha side chain undergoes beta oxidation and the beta side chain undergoes omega oxidation followed by reduction of the ketone to give prostaglandin F analogs.. Misoprostol is extensively absorbed, and undergoes rapid deesterification to its free acid, which is responsible for its clinical activity and, unlike the parent compound, is detectable in plasma. The risk of uterine rupture increases with advancing gestational ages and with prior uterine surgery, including Cesarean delivery.Cytotec is available only as a unit-of-use package that includes a leaflet containing patient information.. . Grand multiparity also appears to be a risk factor for uterine rupture.There may be an increased risk of uterine tachysystole, uterine rupture, meconium passage, meconium staining of amniotic fluid, and Cesarean delivery due to uterine hyperstimulation with the use of higher doses of Cytotec (misoprostol), including the manufactured 100 mcg tablet
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